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Know your Cannabinoids- Cannabigerol (CBG)

Here is what we know about CBG and why it will be everywhere in 2021

Cannabigerol is the “Mother of All Cannabinoids” ….literally. It is the start of synthesis chain of all cannabinoids in the cannabis plant. Although CBG found in trace amounts of cannabis strains and is classified as a minor cannabinoid, it plays a major role cannabinoid synthesis as well as its medicinal properties. CBG could more effectively aid inflammation, allergies, and other common health problems similar to CBD, but better!

In the Cannabis plant, there is a chain of events that result in THC and CBD, the better Here is what we know about CBG and why it will be everywhere in 2021.

In the Cannabis plant, there is a chain of events that result in varying cannabinoids, including the more commonly known THC and CBD. However, there are numerous other cannabinoids which all start off as CBG.

The very first link in this chain is CBG.


Prior to 2021, there were certain hemp and marijuana varieties that showed this cannabinoid in varying amounts. 

In the last couple of years, more scientific approaches to genetic screening have led to the discovery of several genetic mutants that stop the synthesis of cannabinoids at this step, resulting in very high CBG content. 

For example, Oregon CBD’s “White” is a mutation from a popular THC dominant lineage known as “The White”. In previous years especially in illicit grows, these phenotypes would have been discarded because they didn’t get you “High”. 

With the legalization of cannabis and the accompanying spiked interest in “Minor” cannabinoids, these Phenotypes are being selected for their medicinal quality. 

Since the synthesis of CBG to any other cannabinoid is the only thing that is halted, and resin quantity along with total cannabinoids are similar to the parents of this genetic mutation, several varieties of CBG dominant strains have emerged and are capable of hitting 20 percent or more CBG without producing the first bit of THC or CBD. 

In the hemp world, we call these “Unicorns”!

Now that this Cannabinoid is going to be everywhere in 2021 and beyond, what does it do?

Rather than making blanket claims of the medicinal effects of our products, our initiative at Deep Rooted Hemp is to provide you with peer-reviewed information so that you can make your own informed decisions. 

We have known about the Endo-Cannabinoid System (ECS) now for several years. The scientific community is starting to learn about the interaction of these plant-based compounds and the inherent system inside each and every one of us.

Here is our takeaway from a recent journal: 

“Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1–CB2 Heteroreceptor Complexes”

The takeaway and interpretation

  1. CBG is a precursor for CBD and THC
  2. Uses the same receptors (CB1 and CB2) as THC and CBD, thus being a competitor
  3. Has higher affinity to CB2 than CB1 receptor
  4. Even though it uses the same receptors, it is not psychotropic
  5. The cascading effects at the receptor level (in the membrane) and inside the cell (cytoplasm) are still open for interpretation and require further research

Our Synopsis- Once one receptor gets stimulated with THC or even CBD, the consumption of CBG may be able to modulate their action – from improving its effect to inhibiting it completely in the long run/exposure, which is a wide range.

Another concept that we are eager to see explored is that since CBG is the base molecule in the plant, that it can act in the same way in the human body. So the body can turn this base molecule into whatever the body’s ECS needs*** (Not sure if there is anything out in the literature to support this)

There are several theories are that CBG can reduce the anxiety associated with THC consumption, working on the same receptors as THC. 

Some other reported potential benefits of CBG:

  • Reduction of intraocular pressure (Glaucoma)
  • Antibiotic and antibacterial effect (probably, the most efficient cannabinoid in this regard)
  • Prevention of colon carcinogenesis
  • Inhibits growth of cancer cells
  • Inflammations of the digestive system (Crohn's disease, ulcerative colitis, bowel inflammation)
  • Relief of pain and anxiety
  • Neuroprotective properties (multiple sclerosis, Huntington's disease, and other neurodegenerative conditions)
  • Antiseptic properties (treatment of MRSA, Methicillin-resistant Staphylococcus aureus)
  • Inhibits the uptake of GABA (anxiety, muscle tension)
  • Stimulates appetite (cachexia)
  • Stimulates bone formation and healing
  • Antispasmodic effect (Dravet syndrome, epilepsy)

The last word:

What does CBG do for you? We love to hear feedback about our products and how they help you Maintain Your Flow State.

One recent post from a COVID Survivor on Facebook has found relief from our 50:50 CBD:CBG blend.

We have planted two varietals from Oregon CBD: “The White” and “Stem Cell” that we will be observing and documenting on our Instagram and other social outlets this summer from veg to harvest!